THEORETICAL COMPUTATION BACKGROUND FOR TRANSFORMATION OF FOUNDATIONS USING PILE DRAINS


Non-human primates in the PKPD evaluation of biologics: Needs and options to reduce, refine, and replace. A BioSafe White Paper

Monoclonal antibodies (mAbs) deliver great benefits to patients with chronic and/or severe diseases thanks to their strong specificity to the therapeutic target.As a result of this specificity, non-human primates (NHP) are often the only preclinical species in which therapeutic antibodies cross-react with the target.Here, we highlight the value and

read more

Comprehensive Transcriptional Changes in the Liver of Kanglang White Minnow (Anabarilius grahami) in Response to the Infection of Parasite Ichthyophthirius multifiliis

The notorious parasite Ichthyophthirius multifiliis (Ich) has been recorded worldwide in fish species and causes white spot disease, posing major threats and resulting in severe losses to international fish production.Extensively effective strategies for treating Ich are not available yet, and genetic mechanisms of hosts in response to the parasite

read more

Rapid Exercise-Induced Mobilization of Dendritic Cells Is Potentially Mediated by a Flt3L- and MMP-9-Dependent Process in Multiple Sclerosis

In healthy individuals, one exercise bout induces a substantial increase in the number of circulating leukocytes, while their function is transiently suppressed.The effect of one exercise bout in multiple sclerosis (MS) is less studied.Since recent evidence Bar Board suggests a role of dendritic cells (DC) in the pathogenesis of MS, we investigated

read more

Bias by gender: exploring gender-based differences in the endorsement of ADHD symptoms and impairment among adult patients

BackgroundResearch on adult attention-deficit/hyperactivity disorder (ADHD) remains limited, particularly regarding the experiences of women.MethodsThis exploratory study investigates patient responses to the Diagnostic Interview for ADHD in Adults (DIVA-5), which assesses current (adult) and retrospective (childhood) ADHD symptoms based on criteri

read more